From: Kirby Vandivort (
Date: Tue Dec 07 2010 - 11:15:01 CST


It sounds like the 'work' directory for multiseq has been set to c:, which isn't
ideal. Do you have a 'tmp' or 'temp' directory on your c: drive? If not, it
would be best for you to make one, and then set the work directory in multiseq
(from the Multiseq window, select 'File' and then 'Choose work directory...' and
configure your work directory to whatever temp directory you have. Try things
after that. If it still doesn't work, try restarting VMD to make sure that
MultiSeq has "learned" the new directory.


Olimpia Popko wrote:
> Hallo,
> I am getting the following message when I try to run Multiseq under Windows
> Vista.
> The STAMP alignment failed with the following message:
> couldn't open "c:/multiseq-406080740227.start.domain":invalid argument
> Originally I was getting a "permission denied" error but from a previous
> post they suggested changing the permissions under C:/ in the security tab
> under properties. When I changed the permissions to allow me to do
> everything I got the above error message.
> I would appreciate any help.
> Thanks,
> Olimpia.

Kirby Vandivort                      Theoretical and
Senior Research Programmer            Computational Biophysics
Email:          3061 Beckman Institute    University of Illinois
Phone: (217) 244-1928                405 N. Mathews Ave
Fax  : (217) 244-6078                Urbana, IL  61801, USA