Influenza hemagglutinin (HA) is the most abundant surface antigen of the virus. Since there are 18 subtypes of HA with different antigenicity, there is a strong need to develop broadly neutralizing antibodies targeting multiple subtypes. In collaboration with the Wu Lab at the University of Illinois, Resource researchers reconstructed the structure of the complex between HA and a broadly neutralizing antibody on the viral membrane and simulated it with NAMD. The simulation results revealed membrane interactions for the antibody, which were then confirmed by mutagenesis experiments. The results are made recently available as a cover article in Structure and provide a foundation for rational design of more effective antibodies.